Can Amazon AppStream effectively replace OnLive's SL Go? There was a lot of talk around that question recently, and I put it to Cristina Videira Lopes (aka Diva Canto), a Xerox PARC alum who's now an ICS professor at UC Irvine and a longtime innovator in virtual worlds. She deferred on whether AppStream was right to stream Second Life in particular, preferring to talk about using AppStream for commercial applications of virtual environments. (Which she uses, as it happens, for her OpenSim-based world.)
Short version? The main obstacle is cost: At the moment, AppStream costs 83 cents an hour per user, so much more expensive than SL Go. So AppStream is probably not a good fit for extended use -- but appropriate for virtual world use for shorter, business/real world/educational based applications.
Anyway, here's Diva's full breakdown: